Medication non-adherence among older adults with chronic diseases remains prevalent worldwide. WHO identified Intrinsic capacity (IC) as the composite of all the physical and mental capacities of an individual can draw on. Association of medication non-adherence with IC pattern, individual impairments, and levels remains underexplored. A cross-sectional questionnaire-based survey was conducted in 2022 among older adults in southern Taiwan. 905 older adults with chronic diseases were included in this study. The Integrated Care for Older People Screening Tool for Taiwanese and the Adherence to Refills and Medication Scale (ARMS) were used to assess IC and medication non-adherence, respectively. Latent class analysis (LCA) was used to identify impairment patterns of IC and binary logistic regression was used to assess the association between association of intrinsic capacity and medication non-adherence. 176 (19.4%) participants were non-adherent to medication. LCA identified three distinct subgroups with different IC impairment patterns: robust (prevalence: 84.64%), physio-cognitive decline (11.49%), and depression with limited mobility and malnutrition (3.87%). Compared with the robust group, the group with depression with limited mobility and malnutrition was at 2.47 times higher risk for medication non-adherence. Compared with those with no IC impairments, those with hearing loss and depressive symptoms were at 2.27 and 2.04 times higher risk for medication non-adherence, respectively. Compared with those with high IC capacity, those with low IC capacity were 1.88 times higher at risk for medication non-adherence. Intervention for improving medication non-adherence among older adults with chronic diseases should consider IC.

Authors:
Chiachi Bonnie Lee, China Medical University, Taiwan
Hung-Yu Chen, National Cheng Kung University, Taiwan
Hui-Chen Su, National Cheng Kung University, Taiwan
Yi-Lin Wu, National Cheng Kung University Hospital, Taiwan
Yi-Ching Yang, National Cheng Kung University, Taiwan
Chung-Yi Li, National Cheng Kung University, Taiwan

About the Presenter(s)
Dr. Chiachi Bonnie Lee is currently a full associate professor affiliated with the Department of Health Services Administration at China Medical University, Taiwan.

See this presentation on the full schedule – Wednesday Schedule

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