There is an inseparable relationship between diet and intestinal microorganisms. Therefore, studying the relationship between diet quality and intestinal microbial flora is crucial to human health. This study focused on hemodialysis (HD) patients and investigated the association between Healthy eating index-2015 (HEI-2015) and intestinal microbial alpha diversity.
A cross-sectional study using fecal DNA sequencing and three-day 24-hour dietary recall method was conducted on maintenance HD patients who participated in this study. HEI-2015 can be used to assess subjects' compliance with dietary guidelines. According to the median score (41.5) of the subjects' HEI-2015, they were divided into high (41.7~55.8) and low (29.8~41.3) groups, and the correlation between the two groups and the alpha diversity of intestinal microorganisms was explored.
Among 28 HD patients, mean age was 62.4 ± 11.3 years, and 36% were women. Comparing the intestinal microbial alpha diversity in HEI-2015 high group (n = 14) and low (n = 14) group, the results showed no significant difference between the two groups (P = 0.378). In addition, the intestinal microbial alpha diversity were non-significant difference between the high and low groups of the components of HEI-2015: total vegetables (P = 0.585), greens and beans (P = 0.768), fatty acids (P = 0.355), added sugars (P = 0.375) and saturated fat (P = 0.135).
Although the results show that there is no significant difference between HEI-2015 and intestinal microbial alpha diversity, a balanced diet should still be followed to maintain the nutritional needs of human.

Authors:
Wei-Ren Lee, China Medical University, Taiwan
Huey-Liang Kuo, China Medical University Hospital, Taiwan
Chia-Wen Tsai, China Medical University, Taiwan
Po-Ren Hsueh, China Medical University Hospital, Taiwan
Kai-Ling Yang, China Medical University Hospital, Taiwan
Pei-Yu Wu, China Medical University, Taiwan

About the Presenter(s)
Mr. Wei-ren Lee is currently in the second year of the Master's program at the Department of Nutrition at China Medical University.

See this presentation on the full schedule – Tuesday Schedule

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